Tempus to buy cancer test maker Personalis for $1.5 billion

Industry:    6 days ago

Tempus AI said ​on Monday it would buy Personalis in a deal valued at about $1.5 billion, ‌adding a cancer test to the AI-enabled precision medicine firm’s oncology portfolio.

Personalis shares fell 12% in morning trading, while Tempus dropped nearly 9%.

Personalis shareholders will receive $16.25 ​per share, mostly in Tempus stock — a 5.6% premium to ​the last close of the cancer test maker’s shares. Tempus ⁠has the option to pay up to 50% of the deal ​value in cash.

The share prices fell due to the deal’s stock-based ​structure, Guggenheim analyst Subbu Nambi said, adding that Personalis investors remain skeptical about Tempus’ potential upside.

Tempus will gain access to Personalis’ NeXT personal cancer test, which uses ​MRD, or minimal residual disease, technology to detect tiny traces of ​cancer that may remain after surgery, chemotherapy or other treatment and can be ‌too small to appear on scans.

The test creates a personalized genetic signature of a patient’s cancer, which doctors can track over time through blood tests to monitor for remaining or returning disease.

The acquisition expands on an ​existing partnership between ​the companies, ⁠under which Tempus invested in Personalis in November 2023 to develop the NeXT personal test.

“The reason we ​didn’t do this a year or two ago is ​we wanted ⁠to be at the point in the curve where this was going to quickly turn into a really healthy business from a gross ⁠profit and ​a margin perspective,” Tempus CEO Eric Lefkofsky ​said on Monday.

The deal is expected to close in late 2026 or early 2027.

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